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Số người truy cập: 107,029,264

 Synthesis of fluorescent silicon quantum dots for ultra-rapid and selective sensing of Cr(VI) ion and biomonitoring of cancer cells
Tác giả hoặc Nhóm tác giả: Le Minh Tu Phan, Seung Hoon Baek, Thang Phan Nguyen, Kyoung Yeol Park, Siyoung Ha, Rafia Rafique, Suresh Kumar Kailasa, and Tae Jung Park
Nơi đăng: Materials Science and Engineering: C; Số: 93;Từ->đến trang: 429-436;Năm: 2018
Lĩnh vực: Y - Dược; Loại: Bài báo khoa học; Thể loại: Quốc tế
TÓM TẮT
A facile one-step synthetic approach was developed for fabrication of fluorescent silicon quantum dots (Si QDs) and used as a probe for fluorescence detection of hexavalent chromium (Cr (VI)) in environmental water samples. The as-prepared Si QDs exhibit a strong fluorescence emission peak at 520 nm with a quantum yield of 14.2%. The fluorescent Si QDs were rapidly produced by using ascorbic acid as a reductant at 55 °C. The emission peak of Si QDs at 420 nm was effectively quenched upon the addition of Cr(VI). The Si QDs acted as the best fluorescent probe for the detection of Cr(VI) at PBS pH 7.4. The developed probe possessed a good linear correlation (R2 = 0.992) between Cr(VI) concentration (1.25–40 μM) and the (F0-F)/F0 values with a detection limit of 0.65 μM. Furthermore, the Si QDs served as a bio-probe for fluorescence imaging of A549 lung cancer cells and cell viability results confirmed the good biocompatible nature of Si QDs. The as-fabricated Si QDs show several advantages such as rapidity, selectivity and biocompatibility for sensing of Cr(VI) and imaging of A549 cells, which opens a facile analytical platform for environmental and bioimaging applications.
ABSTRACT
A facile one-step synthetic approach was developed for fabrication of fluorescent silicon quantum dots (Si QDs) and used as a probe for fluorescence detection of hexavalent chromium (Cr (VI)) in environmental water samples. The as-prepared Si QDs exhibit a strong fluorescence emission peak at 520 nm with a quantum yield of 14.2%. The fluorescent Si QDs were rapidly produced by using ascorbic acid as a reductant at 55 °C. The emission peak of Si QDs at 420 nm was effectively quenched upon the addition of Cr(VI). The Si QDs acted as the best fluorescent probe for the detection of Cr(VI) at PBS pH 7.4. The developed probe possessed a good linear correlation (R2 = 0.992) between Cr(VI) concentration (1.25–40 μM) and the (F0-F)/F0 values with a detection limit of 0.65 μM. Furthermore, the Si QDs served as a bio-probe for fluorescence imaging of A549 lung cancer cells and cell viability results confirmed the good biocompatible nature of Si QDs. The as-fabricated Si QDs show several advantages such as rapidity, selectivity and biocompatibility for sensing of Cr(VI) and imaging of A549 cells, which opens a facile analytical platform for environmental and bioimaging applications.
[ 2018mse-synthesis of fluorescent silicon quantum dots for ultra-rapid and selective sensing of cr(vi) ion and biomonitoring of cancer cells.pdf ]
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